Anthropic Claude Models Now Run on NVIDIA GB300 in Azure

Anthropic’s Claude models in Microsoft Foundry have become generally available on Microsoft Azure, running on NVIDIA GB300 Blackwell Ultra GPUs.

Claude models gain general availability on Azure infrastructure. The models operate on NVIDIA GB300 NVL72 systems equipped with NVIDIA Quantum-X800 InfiniBand networking. Azure-native enterprises can now build and deploy autonomous and domain-specific AI agents using this setup.

The availability addresses growing demand for computing power as agentic AI drives enterprise innovation and becomes more autonomous. Organizations require specialized agents to accelerate essential business tasks. Strong inference performance and efficiency from the platform reduce total cost of ownership.

Partnership integrates NVIDIA tools into Anthropic's stack. NVIDIA works with Anthropic to extend developer capabilities through this integration. Enterprises gain the ability to equip Claude agents with domain-specific abilities via NVIDIA verified agent skills that leverage accelerated computing.

These tools allow organizations to embed AI agents deeply into their business operations. The agents function as the operating system for the organization. The setup supports autonomous and specialized sub-agents that perform advanced tasks across business domains.

Secure Agent Workspace provides governed deployment blueprint. Enterprises run Claude agents on Azure using the NVIDIA Secure Agent Workspace Reference Design. The design controls identity, network access, credentials and runtime policy at the infrastructure level. This creates a governed environment for autonomous agents.

Announcement builds on prior strategic partnership. The general availability extends the partnership among Microsoft, NVIDIA and Anthropic first announced in November. That agreement aimed to expand enterprise access to Claude models on NVIDIA accelerated computing. Users can begin by visiting Claude in Microsoft Foundry and consulting the Foundry documentation.